MIGELE™ GEL ELECTROPHORESIS UNIT

Detection of hemoglobinopathies in newborns

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OVERVIEW

Migele™ Gel Electrophoresis Unit

Migele™ Gel Electrophoresis Unit works with the RESOLVE™ hemoglobin kit to detect hemoglobinopathies in newborns and adults, including sickle cell disease and other hemoglobin variants and thalassemias. Now, blood screening labs can conduct these crucial, lifesaving screenings with our easy-to-use, cost-efficient, scalable agarose gel electrophoresis solution.

Instrument

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Achieve accurate results easily

Migele™ Gel Electrophoresis Unit
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Migele Gel Electrophoresis Workflow

agarose gel electrophoresis example workflow

How it works

Resolve Gel Electrophoresis kits

RESOLVE kits

RESOLVE kits separate hemoglobins by IEF on a thin agarose gel. The clean separation of Hb F from Hb A permits differentiation of sickle cell anemia (Hb SS) from sickle cell trait (Hb AS).

Due to the specificity and sensitivity of the gels we produce, separation of Hb C from Hb A2 and Hb E, as well as Hb D-Punjab and Hb G-Philadelphia from Hb S, is achieved.

Migele Gel Electrophoresis unit use with Resolve kits

Accurate Results

The RESOLVE hemoglobin kit separates whole blood, cord blood, or dried blood spot specimen for detection of normal and variant hemoglobins by isoelectric focusing. The kit can run on a flatbed electrofocusing unit. This assay is intended for use as an aid in the diagnosis of neonatal and adult hemoglobinopathies.

Migele Gel Electrophoresis results

Results are visual and easily identifiable

The IEF technique combined with the specially formulated gels results in excellent separation of differing hemoglobin bands, allowing you to achieve identifiable results.

Migele Gel Electrophoresis unit designed for accuracy

Time efficient

The RESOLVE kit lets you to complete the run within 60 (small gel, FR-9120) to 90 (big gel, FR-9400, FR-9360) minutes, excluding sample preparation. Multiple electrophoresis units can be run at the same time to produce more results within the same time frame.

Stacked Migele Gel Electrophoresis units to show ease of scaling up

Scalable

A typical setup includes two to four electrophoresis units on one circulating water bath. Expansion of the system is possible with minimal cost. You can even save space by stacking the units on top of each other.

Kits available for Migele™ Gel Electrophoresis Unit

Kits

Resolve™ Hemoglobin kit

Laboratory Management at your finger tips

SOFTWARE
Analyze at scale
SOFTWARE

Specimen Gate® software

Newborn screening software that provides control and monitoring tools for the entire screening process.

Specimen Gate software is designed to simplify the data collection and workflow processes
involved with receiving specimens, screening for abnormalities, managing patient information, generating specimen reports, and following up abnormal and unsatisfactory specimens.

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Articles & Resources

Articles & Resources

Articles & Resources
Interview Webinar
An innovative approach to sickle cell screening in Uganda – Interview with Charles Kiyaga
Newborn
22 Apr 2021

An innovative approach to sickle cell screening in Uganda – Interview with Charles Kiyaga

An innovative approach to sickle cell screening in Uganda - Interview with Charles Kiyaga
Learn More
Webinar
A historical perspective on Sickle Cell Disease: How did we get here?
Newborn
13 Jul 2021

A historical perspective on Sickle Cell Disease: How did we get here?

In her enlightening presentation, Dr. Venée N. Tubman takes a historical perspective on our understanding of Sickle Cell Disease. From African folk beliefs and oral histories, to early clinical observations in the 19th century, to the first newborn screening efforts in the USA in the 1970s, to the present challenges in sub-Saharan Africa. Dr. Tubman discusses how newborn screening could make a great difference in future decades, and what potentially lies ahead. See the presentation for great insights on SCD.
Learn More
Webinar
Consortium on Newborn Screening in Africa: news from Nigeria
Newborn
13 Jul 2021

Consortium on Newborn Screening in Africa: news from Nigeria

Nigeria is severely burdened by Sickle Cell Disease, with an estimated of 150,000 babies born with SCD each year. Many infants do not reach adolescence, however about 70% of deaths could be prevented with low-cost diagnostic and treatment plans. In her presentation, Professor Obiageli Nnodu discusses the future hopes for Nigeria, including ongoing newborn screening projects and learning ways to develop and expand screening programs.
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More resources

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