Articles and resources

Prenatal
14 Mar 2022

Rule-in and rule-out of pre-eclampsia using DELFIA Xpress PlGF 1-2-3 and sFlt-1: PlGF ratio

The objective of this study was to explore and validate thresholds for Placental growth factor (PlGF) and soluble fms-like tyrosine-kinase 1 (s-Flt-1) (as s-Flt-1: PlGF ratio), to rule-in and rule-out disease in women with suspected pre-eclampsia, using DELFIA® Xpress PlGF1-2-3 and sFlt-1 assays. Published in Pregnancy Hypertension, Volume 27, March 2022
Examination of False Positives in Fetal cfDNA Analysis
Prenatal
20 Dec 2021

Examination of False Positives in Fetal cfDNA Analysis

The lecture entitled “Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study) ” was presented by Dr Ritsuko Pooh at the 8th World Congress on Controversies in Preconception, Preimplantation and Prenatal Genetic Diagnosis (CoGEN) in 2021.
Implications of Fetal Fraction measurement variability in NIPS – Webinar & Transcript
Prenatal
24 Nov 2021

Implications of Fetal Fraction measurement variability in NIPS – Webinar & Transcript

The lecture entitled “Implications of fetal fraction measurement variability in NIPS” was presented by Dr Fredrik Persson at the 2021 International Society for Prenatal Diagnosis (ISPD) conference.
Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study)
Prenatal
08 Oct 2021

Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study)

Pooh, R.K.; Masuda, C.; Matsushika, R.; Machida, M.; Nakamura, T.; Takeda, M.; Ohashi, H.; Kumagai, M.; Uenishi, K.; Roos, F.; Persson, F.; Shimokawa, O. Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study). Diagnostics 2021, 11, 1837. https://doi.org/10.3390/diagnostics11101837
Evaluation of repeat testing of a non-sequencing based NIPT test on a Finnish general-risk population
Prenatal
07 Sep 2021

Evaluation of repeat testing of a non-sequencing based NIPT test on a Finnish general-risk population

Karlsson F, Ahola T, Dahlberg J, Prensky L, Moilanen H, Spalding H. Evaluation of repeat testing of a non- sequencing based NIPT test on a Finnish general- risk population. Acta Obstet Gynecol Scand. 2021;100:1497–1500. https://doi.org/10.1111/aogs.14125
Understanding Fetal Fraction in cfDNA screening
Prenatal
30 Aug 2021

Understanding Fetal Fraction in cfDNA screening

Fetal fraction has been used by some laboratories to determine if they can have confidence in their results. However, there are significant factors to consider when determining its merit, including assay precision, the accuracy of a reported fetal fraction metric and the implications of using a fetal fraction cutoff. In the enclosed publication, we present the science, the data and the impact of using the fetal fraction metric within a clinical context.
Improved outcomes through pre-eclampsia management: Different solutions for different needs
Prenatal
03 Aug 2021

Improved outcomes through pre-eclampsia management: Different solutions for different needs

Professor Jon Hyett, Head of High-Risk Obstetrics and a Senior Staff Specialist in Obstetrics, and Maternal and Fetal Medicine Royal Prince Alfred Hospital, Sydney, Australia
Evaluation of Vanadis system as an alternative method for cell-free fetal DNA assay in maternal plasma
Prenatal
22 Jun 2021

Evaluation of Vanadis system as an alternative method for cell-free fetal DNA assay in maternal plasma

Imma Mercadé, Robin Wijngaard, Javier Laguna, Maria Rodriguez, Elena Casals. Servicio de Bioquímica y Genética Molecular, CDB, Hospital Clínic de Barcelona. Poster presented at the ECPM conference 2021.
Performance of commercially available placental growth factor tests in women with suspected preterm pre‐eclampsia; the COMPARE study
Prenatal
09 Jun 2021

Performance of commercially available placental growth factor tests in women with suspected preterm pre‐eclampsia; the COMPARE study

F.P. McCarthy et. al. Ultrasound in Obstetrics & Gynecology
Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin on length of stay in the neonatal intensive care unit
Prenatal
09 Jun 2021

Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin on length of stay in the neonatal intensive care unit

David Wright et. al. The American Journal of Obstetrics & Gynecology
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